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In a study by Chen et al

1 Introduction Osteomyelitis is a severe infectious disease of bone tissue characterized by progressive inflammatory destruction and new bone formation

Such a control sample may comprise any suitable sample, including but not limited to a sample from a subject (e.g., a subject with monocytes and/or macrophages and/or a control cancer patient with known results (which may be a stored sample or a previous sample measurement))

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doi: 10.1038/s41598-019-56113-7 3